- Thunderbolt & USB
  - Fireface UFX+
    - 188-Channel, 24-Bit/192kHz high-end USB & FireWire Audio Interface
- Firewire & USB
  - Fireface UFX II
    - 60-Channel, 24-Bit/192kHz high-end USB Audio Interface
  - Fireface UCX
    - 36-Channel, 24-Bit/192kHz high-end USB & FireWire Audio Interface
  - Fireface 802
    - 60-channel High-end 192 kHz USB/Firewire audio interface
  - Babyface Pro
    - 24-Channel, 192kHz Bus-powered USB High Speed Audio Interface
  - Fireface UC
    - 36-Channel, 24-Bit/192kHz USB High Speed Audio Interface
  - Digiface USB
    - 66-Channel, 24-Bit 192 kHz bus-powered USB Audio Interface
  - Digiface Dante
    - Bus-Powered Dante and MADI Audio Interface
  - Digiface AVB
    - Bus-Powered AVB USB Audio Interface
- PCI Express
  - HDSPe AIO
    - 38-Channel 24-bit/192kHz PCI Express Card
  - HDSPe RayDAT
    - 72-Channel 192 kHz ADAT/AES PCI Express Card
  - HDSPe PCI Card
- PCI Card
  - HDSP 9652
    - 52-Channel 96 kHz PCI card (ADAT, SPDIF, MIDI)
  - HDSP 9632
    - 32-Channel 24-Bit/192kHz PCI Card
- MADI & AES/EBU
  - MADIface XT
  - MADIface Pro
  - MADIface USB
  - HDSPe MADI FX
    - 390-Channel 192 kHz triple MADI PCI Express card
  - HDSPe MADI
    - 128-Channel 192 kHz MADI PCI Express card
  - HDSPe MADIface
    - 128-Channel 192 kHz MADI PCI ExpressCard for notebook computers
    - 128-Channel 192 kHz MADI PCI ExpressCard for notebook computers
  - HDSPe AES
    - 32-Channel 192 kHz AES/EBU PCI Express card
  - MADI Router
  - MADI Converter
    - 6-fold MADI Optical-BNC/BNC-Optical converter
  - ADI-642
    - 8-Channel 192 kHz MADI <> AES/EBU format converter with 72 x 74 Routing Matrix
  - ADI-6432 / ADI-6432R
    - Bidirectional 64-Channel 192 kHz MADI <> AES/EBU format converter
  - ADI-6432R BNC
    - Bidirectional 64-Channel 192 kHz MADI <> AES-3id format converter
  - ADI-648
    - 64-Channel 192 kHz ADAT/MADI format converter
- Converters
  - M-32 / M-16 AD
  - M-32 / M-16 DA
  - M-32AD Pro
  - M-32DA Pro
  - ADI-8QS
    - 192 kHz 8-Channel High-End AES/EBU ADAT MADI AD/DA converter
  - ADI8-DS MKIII
  - ADI-2 Pro FS
    - High-Performance 768 kHz 2-Channel ADAT.SPDIF.AES/EBU AD/DA converter
  - ADI-2 DAC
    - Ultra-Fidelity PCM/DSD 768 kHz DA converter
  - ADI-2
    - High-Performance 192 kHz 2-Channel ADAT.SPDIF.AES/EBU AD/DA converter
  - ADI-192 DD
    - 192 kHz 8-Channel AES/EBU.ADAT.TDIF Format/Samplerate-Converter
  - ADI-4 DD
    - 8-Channel 24-Bit/96kHz AES.ADAT format converter
- Mic Preamps
  - DMC-842
    - 24-Bit/192kHz 8-Channel AES42 Interface for Digital Microphones
  - Micstasy
    - 24-Bit/192kHz 8-Channel Full Range Preamp & AD converter
  - OctaMic XTC
  - OctaMic II
    - 8-Channel MicPreamp and AD converter to AES/EBU & ADAT
  - QuadMic II
    - 4-Channel MicPreamp
- RME Accessories
  - ARC USB
    - External monitoring remote for all TotalMix FX devices
  - BOB-32
  - BOB-16
  - DTOX-32
  - DTOX-16
  - Cables & Adapters
  - Rackmounts
  - Expansion Boards
    - HDSPe MADI FX OPTO-X
    - HDSP TCO
      
      Optional Hammerfall DSP synchronization module
    - AIS 4/192, AOS4/192
    - HDSP9632WCM
- Discontinued
  - ADI-2 Pro Anniversary Edition
    - High-Performance 768 kHz 2-Channel ADAT.SPDIF.AES/EBU AD/DA converter
  - Advanced Remote Control (ARC)
  - Basic Remote Control (BRC)
  - Babyface
    - 22-Channel, 192kHz Bus-powered USB High Speed Audio Interface
  - Fireface 800
    - 56-Channel, 24-Bit/192kHz Firewire Audio Interface
  - Fireface 400
    - 36-Channel, 24-Bit/192kHz, Bus Powered Mobile Firewire Audio Interface
  - OctaMic (D)
    - 8-Channel MicPreamp
  - ADI-8DS
    - High-Precision 8-Channel 96 kHz ADAT.TDIF AD/DA converter
  - Fireface TCO
    - Optional Fireface 800 synchronization module
  - MADI Bridge
    - 8 x 64-Channel MADI Switcher/Router
  - Fireface UFX
    - 60-Channel, 24-Bit/192kHz high-end USB & FireWire Audio Interface
- A32 Dante
- A32
- A16 MKII
- B4000+